Dr. Ohhira Probiotics Professional Formula has identical ingredients to Dr. Ohhira's Probiotics Original Formula but fermented an additional two years from 3 years to 5 years. Tweaked during the fifth year of processing to provide organic acids that are more robust than those contained in the Dr. Ohhira's Probiotics Original Formula. In addition, the potency of the micronutrient by-products is maximized to expedite the adhesion of the good bacteria in the colon. The CFU of the lactic acid bacteria may be less than in the Original Formula due to the natural variation of ingredients and the more complex manufacturing process. The Professional Formula is recommended for those individuals with a specific health condition.